From the monthly archives:

October 2009

Inverse size-exclusion chromatography

October 23, 2009

The inverse application of the size-exclusion chromatography (SEC) concept, inverse size-exclusion chromatography (ISEC) [1], utilizes a set of molecular probes with defined sizes to determine pore dimensions, and is also referred as chromatographic porosimetry [2].

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Stationary phase: superficially porous particles

October 22, 2009

Superficially porous particles with thicker outer shells were used extensively for liquid-liquid chromatography [1] and as the support for early bonded-phase packings in reverse phase HPLC [2].

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Stationary phase: non-porous particles

October 20, 2009

It is known that the kinetics of mass transfer in wide pore bonded silica can be slow, because of restricted intraparticle diffusion and, furthermore, remaining active surface sites can give rise to undesired interactions.

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Control of porous properties in organic polymer monoliths

October 20, 2009

Many applications of porous materials in areas such as catalysis, adsorption, ion exchange, chromatography, and solid phase synthesis rely on the intimate contact with a surface that supports the active sites.

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Pore formation in organic polymer monoliths

October 19, 2009

The generally accepted mechanism of pore formation in organic polymer monolihts during a typical polymerization in the presence of a precipitant is following [1,2]:

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Monolithic stationary phases

October 18, 2009

As a new type of chromatographic stationary phase, monoliths have been subjected to intensive study in the last years. They differ from other supports mainly in their characteristic structure, which results in the improved chromatographic properties.

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