From the category archives:

Chromatography

Chromatographic coffee cup – do it yourself

July 26, 2010

Recently, I was browsing amazon.com products related to the chromatography keyword. To my big surprise, the number ten (at least in my results) was a “16 oz. Double Wall Insulated Tumbler with chromatography column alone – Paper Insert”.
This is what I call a present for a chromatographer!
I waited until our next order (Harry Potter Playstation [...]

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High temperature vs. Ultra high pressure liquid chromatography

May 2, 2010

The last CASSS Discussion group focused on the possible advantages and disadvantages of high temperature and/or high pressure in a liquid chromatography. The Discussion group was hold as a debate – two experts against each other. The high temperature approach was defended by Nebojsa M. Djordevic (SANO CRO) and Michael W. Dong (Genetech) advocated the [...]

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Costless improvement of your HPLC instrument

April 12, 2010

The recent progress in the column development brought to the market new type of highly efficient columns. These columns can be use either with standard HPLC instruments or with the instruments allowing separations at ultra high pressure (900 MPa). The conventional size of the column (150 x 4.6 mm) has been decreased significantly. The typical [...]

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WebEx. The future of instrumental services?

January 31, 2010

I had to solve connection problem in between the Bruker MS and Agilent LC (Agilent shutdown). On the very end, I found out there was no problem in their mutual communication. However, it shows me the future of the instrumental services. WebEx communication.

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Agilent 1100 shutdown

January 18, 2010

From time to time, we all face problems with HPLC instruments. Then, we all search the internet for the solution for our problem. In this troubleshooting section I would like to point out my problems with instruments and their solutions. Hopefully, it can help also you.
Recently, I was asked to run the HPLC-MS instrument which [...]

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Inverse size-exclusion chromatography

October 23, 2009

The inverse application of the size-exclusion chromatography (SEC) concept, inverse size-exclusion chromatography (ISEC) [1], utilizes a set of molecular probes with defined sizes to determine pore dimensions, and is also referred as chromatographic porosimetry [2].

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Stationary phase: superficially porous particles

October 22, 2009

Superficially porous particles with thicker outer shells were used extensively for liquid-liquid chromatography [1] and as the support for early bonded-phase packings in reverse phase HPLC [2].

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