Superficially porous particles with thicker outer shells were used extensively for liquid-liquid chromatography [1] and as the support for early bonded-phase packings in reverse phase HPLC [2]. Structure of particles Nowadays superficially porous particles typically have a 5-µm solid core and a ~ 0.25 – 1 µm thick outer shell with 30-nm pores. But, the thinner the shell, the [...]
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