The last CASSS Discussion group focused on the possible advantages and disadvantages of high temperature and/or high pressure in a liquid chromatography. The Discussion group was hold as a debate – two experts against each other. The high temperature approach was defended by Nebojsa M. Djordevic (SANO CRO) and Michael W. Dong (Genetech) advocated the [...]
In liquid chromatography liquid mobile phase flows through the column with stationary phase. The main principle of separation remains the same. Compounds have different affinity to the stationary phase and are separated while flowing through the column. The compounds separated with liquid chromatography are disolved in the mobile phase. They have lower difussion coefficients than [...]
Chromatography is analytical chemistry method which is used (and useful) for the separation of complex mixtures of chemical compounds. The main mechanism of the separation is repeatable distribution of the tested compound in between two different phases. Usually, one phase is solid, fixed in the separation device and the other is moving and flows through [...]
Analytical chemist. Amateur photographer. Occasional traveler. Lazy graphoman. Wannabe entertainer. Boring moralist ...
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Chromatographic articles