One of my colleagues has been recently searching for the job in chemistry. After a post-doc at Lawrence Berkeley Laboratory (which can be rightly supposed as one of the most prestigious scientific institution in the world) she is gathering several job talk experience and was so kind to share them with me.
The inverse application of the size-exclusion chromatography (SEC) concept, inverse size-exclusion chromatography (ISEC) [1], utilizes a set of molecular probes with defined sizes to determine pore dimensions, and is also referred as chromatographic porosimetry [2].
Superficially porous particles with thicker outer shells were used extensively for liquid-liquid chromatography [1] and as the support for early bonded-phase packings in reverse phase HPLC [2].
It is known that the kinetics of mass transfer in wide pore bonded silica can be slow, because of restricted intraparticle diffusion and, furthermore, remaining active surface sites can give rise to undesired interactions.
Many applications of porous materials in areas such as catalysis, adsorption, ion exchange, chromatography, and solid phase synthesis rely on the intimate contact with a surface that supports the active sites.